The wheel and axle is a modification of the pulley in which the center pin (axle) is attached to the wheel.  Turning the wheel through a long distance with a weak force turns the axle through a shorter distance with a strong force.  Alternately, one can turn the axle with a strong force through a short distance and get the wheel to turn farther with a weak force.
 

Examples of wheels and axles:

• A steering wheel
• The wheels and axle on a cart
• The wheels and axle on a self-propelled vehicle (turned by a mousetrap and transfers power to the wheels)
• A knob on a stove